Има промяна в броя на групите за следните специалности и курсове (поток) за учебната 2016/2017 г.:
Информатика, 2 курс
Информатика, 3 курс
Информатика, 4 курс
Компютърни науки, 3 курс, поток 2
Математика и информатика, 3 курс
Новото разпределение по групи ще става чрез системата СУСИ, чрез техническа кампания за избираеми дисциплини – за избор на група, от 12-и до 18-и септември (включително) 2016 г.
На студентите от посочените специалности се дава възможност сами да изберат в коя група да бъдат, като се запишат за избираема дисциплина със съответното име – "Избор на група – специалност…, курс…, ….гр.", в модула за избираеми дисциплини. Заложени са ограничения за броя на записалите се, естествени за размера на групите.
Всеки студент от съотвените специалности може да се запише само за една избираема дисциплина (група).
Студентите от специалност Математика и информатика, 3 курс, не избират група –групата е една и ще бъдат записани служебно.
Студентите, които не се запишат (не изберат група), ще бъдат разпределени по групи служебно след края на техническата кампания и няма да могат да искат промяна на групата.
Студентите извън тези специалности и курсове (и поток) не записват служебни ИД.
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cjc1295 ipamorelin side effects · 25.09.2025 г. на 13:05 ч.
CJC-1295 Side Effects, Complications, And Risk Profile
CJC‑1295 Side Effects, Complications, And Risk Profile
The peptide CJC‑1295 has attracted attention for its potential benefits in growth hormone release, body composition, and overall health.
However, like all pharmacological agents, it carries a spectrum of side effects and risks that users must understand before considering its use.
Research Based
Extensive preclinical studies in rodents and small human trials have explored CJC‑1295’s efficacy and
safety. These investigations reveal that while the peptide
can elevate circulating growth hormone levels, the long‑term implications for humans remain uncertain due to limited large‑scale clinical data.
What is CJC‑1295?
CJC‑1295 is a synthetic analogue of growth hormone‑releasing hormone (GHRH).
It stimulates the pituitary gland to secrete more endogenous growth hormone and insulin‑like
growth factor 1 (IGF‑1), which are key regulators of metabolism, muscle growth,
and tissue repair.
Mechanism of Action
Unlike exogenous growth hormone injections, CJC‑1295 binds to GHRH receptors on pituitary cells.
This interaction triggers a cascade that increases the release of
growth hormone in a pulsatile manner. The peptide’s design includes modifications that extend its half‑life, allowing for
less frequent dosing while maintaining sustained hormone elevation.
Legal Status
In many jurisdictions, CJC‑1295 is classified as a research chemical and is not approved for therapeutic use
by regulatory agencies such as the FDA or EMA. Its sale for human consumption is typically prohibited, though
it may be available through underground channels or specialized peptide suppliers
that claim „research only“ status.
CJC‑1295 Benefits
Clinical reports suggest several potential advantages:
Enhanced lean muscle mass and strength.
Improved recovery from exercise and injury.
Modulation of body fat distribution, potentially aiding in weight
loss.
Support for sleep quality due to growth hormone’s role
in restorative processes.
CJC‑1295 and Sleep
Growth hormone is predominantly secreted during deep sleep stages.
By boosting endogenous levels, CJC‑1295 may help prolong
slow‑wave sleep, thereby improving overall sleep architecture and daytime alertness.
CJC‑1295 and Muscle Growth
Increased IGF‑1 production stimulates satellite
cell activity and protein synthesis within skeletal muscle fibers.
Users often report gains in muscle thickness and reduced
time needed to recover between workouts.
CJC‑1295 and Fat Loss
Elevated growth hormone enhances lipolysis, the breakdown of triglycerides
into free fatty acids for energy use. Over time, this can shift body composition toward a
higher ratio of lean mass to fat tissue.
CJC‑1295 Side Effects
Common adverse reactions include:
Water retention leading to edema or bloating.
Joint and muscle aches.
Temporary increases in appetite.
Injection site irritation or discomfort.
Less common but more serious effects may involve
altered glucose metabolism, which could impact insulin sensitivity,
especially in individuals with pre‑existing metabolic
conditions.
CJC‑1295 Dosage Guide
Typical research protocols recommend 100–250 µg per
injection, administered once or twice daily depending on the desired serum levels
and individual response. Users should start at the lower end of
this range to assess tolerance before titrating upward.
Sample CJC‑1295 DAC Dosing Protocol
A frequently cited regimen involves:
Day 1–21: 150 µg subcutaneously once daily.
Day 22–28: 200 µg twice daily (morning and evening).
Continue monitoring hormone levels and side effects throughout
the cycle.
Research CJC‑1295 Cycle
A standard 12‑week cycle may be followed by a two‑to‑four‑week break to mitigate
potential receptor downregulation. Some protocols pair the peptide with complementary
agents such as Ipamorelin or growth hormone secretagogues
for synergistic action.
CJC‑1295 + Ipamorelin
Combining CJC‑1295 with cjc1295 ipamorelin side effects, a selective ghrelin receptor agonist, can produce a more robust and
sustained release of growth hormone. This pairing is popular among users seeking
maximal anabolic effects while minimizing side effect burden.
Where to Buy CJC‑1295 Online? 2024 Edition
Peptide suppliers in the United States often list „research chemical“ versions of CJC‑1295 for purchase,
typically under a DAC (Drug Affinity Complex) designation that extends
half‑life. Buyers should verify supplier credibility and ensure the product’s purity
via third‑party testing.
CJC‑1295 No DAC Limitless Life
Some vendors offer a non‑DAC variant marketed as „Limitless Life,“ claiming similar efficacy with reduced cost.
However, without the extended half‑life, dosing
frequency may increase, potentially raising injection-related side effects.
peptidesorg10
A popular online community for peptide users shares experiences and dosage tips.
Members often discuss CJC‑1295 protocols, allowing newcomers to gauge real‑world outcomes.
CJC‑1295 DAC Research Chemical
The DAC form of CJC‑1295 is favored in research settings due to its stability and prolonged activity.
Laboratories use it primarily to study growth hormone pathways rather than for therapeutic
purposes.
Side Effects of CJC‑1295 Verdict
While many users report minimal discomfort, the peptide’s
influence on hormonal balance can pose risks such as fluid retention, joint pain, or impaired
glucose tolerance. Long‑term safety data are lacking, so caution and regular medical monitoring are advised.
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best anavar dosage for men · 25.09.2025 г. на 21:08 ч.
Best Anavar Dosage For Men And Women: How Much To Take For Cycle?
Subscribe to Updates
Stay informed about the latest research, dosage recommendations,
and best practices for using Anavar safely and effectively.
Sign up with your preferred newsletter or follow our social media channels for weekly insights.
The Proper Way to Use the Anavar Steroid in Bodybuilding and
Steroid Cycles
Anavar (Oxandrolone) is a mild anabolic agent that promotes lean muscle gains while minimizing water retention. To use it responsibly,
begin by determining whether you are a beginner, intermediate, or
advanced athlete. Establish a clear goal—strength, cutting, or maintenance—and align your dosage accordingly.
Always pair Anavar with a structured training program
and a nutrition plan rich in protein and balanced macros.
The Dosages, Cycles, and Results of Anavar for Women Bodybuilders
and Athletes
Women typically start at 10–20 mg/day due to lower androgen sensitivity.
A 6‑week cycle is common, yielding noticeable muscle
definition without excessive masculinization. Results include increased lean body mass,
improved recovery rates, and a smoother cutting phase.
Defining the Best Anavar Dosage: Male & Female Cycle Success
For men, doses of 20–40 mg/day over 8–10 weeks strike a balance between efficacy and safety.
Women should limit themselves to 10–15 mg/day for
6 weeks. Adjustments depend on individual tolerance, training intensity, and prior steroid
exposure.
Anavar Cycle Logs for Bodybuilders, Beginners, and Every Gender!
Tracking daily intake, body weight changes,
strength metrics, and subjective well‑being helps refine future cycles.
Log your workouts, meals, sleep hours, and any side
effects to identify patterns that influence performance.
Anavar Cycles: Celebrity Secrets Every Beginner Needs To Know
Top athletes often use a 10–20 mg/day dose for 8 weeks, sometimes paired with natural
supplements like creatine or branched‑chain amino acids.
They emphasize consistent training and strict diet adherence to maximize
Anavar’s benefits while mitigating risks.
Discover the Fitness World’s Best Kept Secret:
Anavar Australia
Australia’s regulatory framework allows medical prescriptions of Anavar for specific conditions, yet many athletes import it
through legitimate pharmacies. Awareness of local laws is essential to avoid legal pitfalls.
Understanding Anavar: An Overview
Oxandrolone is a synthetic derivative of dihydrotestosterone (DHT).
It binds strongly to androgen receptors, stimulating protein synthesis and nitrogen retention while
sparing the liver compared to other steroids.
Benefits of Anavar for Fitness and Bodybuilding
Rapid lean muscle gains
Reduced water retention
Enhanced strength without significant weight increase
Supportive effects on recovery
Anavar for Bodybuilding
In bodybuilding, Anavar is prized for its ability to sculpt a „cut“ physique.
It preserves muscle during caloric deficits, allowing athletes to shed fat
while retaining density.
Anavar’s Role in Bodybuilding
Its anabolic potency combined with low androgenicity makes it
suitable for final stages of a cutting cycle, helping athletes achieve a razor‑thin look without sacrificing performance.
Choosing the Right Anavar Dosage for Bodybuilding
Consider your body weight, training load, and desired outcome.
A conservative start followed by incremental increases allows
you to gauge tolerance before hitting peak dosage.
Anavar and Cutting Cycle
During a cutting phase, Anavar enhances fat oxidation and
preserves muscle mass. Pairing it with a moderate caloric deficit maximizes results.
Anavar for Fat Loss and Cutting
By boosting basal metabolic rate, Anavar accelerates calorie burn. Combined with high‑intensity interval training (HIIT), users often report faster fat loss.
Optimal Anavar Dosage for Cutting
For men: 20–30 mg/day over 8 weeks. For women: 10–15 mg/day over 6
weeks. Monitor body composition to avoid plateauing.
Understanding Oxandrolone Dose
Oxandrolone dosage depends on whether the goal is maintenance, cutting,
or strength. The drug’s side‑effect profile remains mild compared to other anabolic
agents.
The Basics of Oxandrolone
Oral administration
Low androgenic activity
Minimal estrogen conversion
Appropriate Oxandrolone Dose for Bodybuilding
Beginners often start with 10 mg/day; experienced users may
reach up to 40 mg/day. The decision hinges on prior steroid experience and tolerance.
Anavar Dosage in Combined Cycles
When stacked, Anavar’s dose typically reduces by 20–30% to avoid
cumulative side effects. For instance, if you’d use 40 mg/day alone, pair it with 25–30 mg/day when combined.
Anavar and Winstrol Cycle Optimal Dosages
A common stack: 10–15 mg Anavar + 25–50 mg Winstrol for 8 weeks.
The synergy enhances lean muscle retention while cutting fat.
Anavar and Primobolan Dosage Bodybuilding
Stacking Anavar (10–20 mg/day) with Primobolan (200 mg every other day)
creates a potent yet relatively mild anabolic effect ideal for advanced
cutters.
Anavar for Women: An In-Depth Look
Women’s bodies are more sensitive to androgenic
activity. Therefore, lower doses and shorter cycles mitigate
the risk of virilization while still providing muscle‑defining benefits.
Why Anavar is Suitable for Women
Its low androgenicity reduces side‑effects like hirsutism
or voice deepening. It also promotes lean mass without significant
water retention, aligning with women’s aesthetic goals.
Guidance on Anavar Dose for Women
Start at 5 mg/day and assess tolerance after a week.
Increase to 10–15 mg/day only if no adverse effects appear.
Practical Tips for Anavar Dosage
Use a reliable scale to measure doses accurately.
Split the daily dose into two or three smaller portions.
Monitor blood pressure and liver enzymes if you plan extended use.
Cautions and Side Effects of Anavar
Mild androgenic symptoms (acne, hair loss).
Liver strain at high doses or prolonged use.
Hormonal suppression may occur; post‑cycle therapy can help restore balance.
Availability and Legal Status of Anavar
In many countries, Anavar is classified as a prescription medication for medical conditions such as weight loss in cachectic patients.
Recreational use often requires purchase through underground channels, posing legal and safety risks.
Anavar Dosage: Tailor-fit for Specific Sports
Sports requiring rapid muscle gain or weight maintenance benefit from higher doses, while endurance athletes need lower, sustained levels to preserve stamina.
Anavar Dosage for Strength Sports
Athletes in powerlifting or Olympic lifting can use
20–30 mg/day during a short cycle to increase maximal strength without bulk.
Suitable Anavar Dosage for Endurance Sports
Endurance athletes might take 10–15 mg/day to support muscle repair while keeping body weight minimal.
Final Thoughts on Anavar Dosage
The key to success with Anavar lies in individualized dosing,
meticulous tracking, and adherence to a balanced training and nutrition plan. Starting conservatively allows you to gauge tolerance and adjust accordingly.
Frequently Asked Questions (FAQ)
What is the typical duration of an Anavar cycle for men?
An 8‑to‑10‑week cycle is standard for men, though some use it in shorter 6‑week cuts.
What is a typical Anavar cycle for women?
Women generally run a 6‑week cycle at 10–15 mg/day.
Can Anavar be stacked with other steroids?
Yes; common stacks include Winstrol, Primobolan,
or testosterone. However, careful dose management is essential to avoid side effects.
How long until I see results with Oxandrolone?
Initial gains in muscle hardness and strength can appear within 4–6 weeks, but
significant fat loss may take longer.
Is Anavar suitable for beginners in bodybuilding?
Beginners can use it, but they should start at the lower end of the dosage range (10 mg/day) to assess tolerance.
Are diet and workout important when taking Anavar?
Absolutely. A protein‑rich diet combined with progressive resistance training maximizes Anavar’s anabolic potential while minimizing unnecessary fat gain.
What does anabolic Mean · 26.09.2025 г. на 14:04 ч.
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sustanon dianabol deca cycle · 26.09.2025 г. на 18:03 ч.
Anabolic Steroids: Uses, Side Effects, And Alternatives
# Anabolic Steroids – A Comprehensive Guide
Anabolic steroids are synthetic derivatives of the male sex hormone **testosterone**.
They’re designed to mimic or amplify testosterone’s effects
on muscle and bone growth, while also suppressing some of its negative side‑effects.
Although they can provide rapid gains in strength and size, anabolic steroids carry significant health risks that far outweigh the short‑term benefits for most people.
–
## 1. What Are Anabolic Steroids?
| Term | Meaning |
|––|–––|
| **Anabolic** | Promotes cell growth & protein synthesis (muscle building).
|
| **Steroid** | Chemical structure based on a four‑ring core.
|
| **Synthetic derivative** | Lab‑made version of testosterone or other natural hormones.
|
### Common Types
– **Testosterone esters** (e.g., Testosterone cypionate, enanthate)
– **Dihydrotestosterone derivatives** (e.g.,
DHT, stanozolol)
– **Selective androgen receptor modulators (SARMs)** – a newer class with similar effects but different safety profiles.
## 2. Why People Use Them
| Goal | Typical Users |
|––|–––––|
| **Gain muscle mass & strength** | Bodybuilders, athletes
|
| **Improve athletic performance** | Powerlifters, sprinters |
| **Enhance recovery and reduce injury risk**
| Competitive sports teams |
| **Offset hormonal decline (e.g., testosterone deficiency)** | Men with
hypogonadism |
### Important: The use of anabolic agents outside prescribed medical indications is often illegal in many countries.
In the United States, they are regulated as Schedule III controlled
substances under the Controlled Substances Act.
## 3. How They Work – A Quick Overview
1. **Anabolic Steroids**
– Synthetic derivatives of testosterone that can bind to androgen receptors in muscle
cells.
– Trigger gene transcription leading to increased protein synthesis (muscle
growth) and reduced protein breakdown.
2. **Growth Hormone‑Releasing Peptides (e.g., GHRP‑6, Ipamorelin)**
– Bind to the ghrelin receptor on pituitary cells, stimulating secretion of growth hormone.
– Indirectly increase insulin‑like growth factor 1 (IGF‑1) levels in the liver.
3. **Peptide Hormones (e.g., Sermorelin, CJC‑1295)**
– Mimic natural releasing hormones or act as analogues to prolong release
of growth hormone from pituitary cells.
4. **Cyclic Peptides**
– Designed for improved metabolic stability and oral bioavailability;
e.g., cyclohexapeptide analogues that resist peptidase degradation.
–
## 3. Current Clinical Uses
| Category | Approved or Widely Used Indications | Key Points |
|–––-|––––––––––––-|––––|
| **Anabolic Steroids** | *Glucocorticoid‑induced osteoporosis*, severe
weight loss in HIV, some myopathies; used off‑label for performance enhancement.
| Long‑term use requires careful monitoring of lipid profile, liver enzymes, blood pressure, mood changes.
|
| **Peptide Hormones** | • Growth hormone‑releasing peptides (GHRPs) –
treat growth hormone deficiency.
• Follicle‑stimulating hormone (FSH)/LH analogs – infertility treatment.
• Parathyroid hormone fragments – osteoporosis. | Requires injection; possible
local irritation, systemic side effects like edema, hyperglycemia.
|
| **Therapeutic Peptides** | • Insulin analogs – diabetes mellitus.
• Bradykinin inhibitors – hypertension.
• Antimicrobial peptides – topical infections.
| Mostly safe with known profiles; insulin analogues have hypoglycemia risk.
|
–
## 3. Current Trends and Potential Developments in Pharmaceutical Chemistry
| Trend / Innovation | Relevance to Pharmacy Practice | Impact on Drug Development |
|–––––––|–––––––––––|–––––––––-|
| **Peptide‑based Drugs** (including antibody‑drug conjugates, GLP‑1 analogues) | New therapeutic options for chronic diseases; requires understanding of stability and formulation. | Drives need for advanced analytical methods
and excipient research. |
| **Prodrugs and Bioactivatable Compounds** |
Allows targeted delivery and reduced side‑effects.
| Expands the toolbox for medicinal chemists to modulate PK/PD profiles.
|
| **Nanotechnology & Controlled Release Systems** | Improves patient adherence; can deliver drugs across
barriers (e.g., BBB). | Requires interdisciplinary collaboration between chemists,
pharmacists, and materials scientists. |
| **Computational Drug Design & AI‑Driven Predictions** |
Accelerates lead optimization. | Necessitates integration of
cheminformatics into traditional workflows. |
–
## 4. Proposed Research Plan
### 5.1 Objective
To develop a **biocompatible, injectable hydrogel system capable of sustained release of a model
peptide therapeutic (e.g., GLP‑1 analog)**,
achieving a 48–72 h release profile while preserving bioactivity.
### 5.2 Strategy Overview
– **Hydrogel Composition**: Use a dual‑crosslinking approach combining:
– *Physical* crosslinks via host–guest interactions between β‑cyclodextrin (β‑CD) and adamantane‑modified polymers.
– *Chemical* covalent crosslinks via Michael addition of multi‑armed
PEG‑acrylate to thiol groups on peptide‑bearing chains.
– **Peptide Conjugation**: Attach the peptide to a short PEG linker bearing a cysteine residue, enabling site‑specific attachment without compromising function.
– **Controlled Degradation**: Incorporate ester bonds within polymer backbone that hydrolyze at physiological pH, releasing the peptide gradually.
– **Mechanical Properties**: Tune the ratio of host–guest to covalent crosslinks to achieve a storage
modulus (G′) ≈ 500 Pa, matching brain tissue stiffness.
**Design Rationale**
– *Host–Guest Interactions*: Provide reversible, dynamic crosslinks that allow
local remodeling during cell migration while maintaining overall
structural integrity.
– *Covalent Crosslinks*: Offer long‑term mechanical stability essential for sustained
culture and imaging over days to weeks.
– *Ester Linkages*: Enable predictable hydrolysis rates (~days),
ensuring controlled release of encapsulated peptides without abrupt concentration spikes.
– *Mechanical Tuning*: By adjusting crosslink densities,
the scaffold’s viscoelastic properties can be matched to specific brain regions (e.g.,
softer white matter vs. stiffer gray matter).
–
## 4. Implementation Blueprint
### A. Materials and Equipment
| **Component** | **Specification / Supplier** |
|–––––|––––––––––|
| Gelatin Type B (≥75 % bloom) | Sigma-Aldrich, G4510
|
| N,N′-Dicyclohexylcarbodiimide (DCC) | Sigma-Aldrich,
DCC-1 |
| 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) | Thermo Fisher Scientific, HPH400 |
| Sodium chloride | Millipore Sigma, NaCl |
| Dimethyl sulfoxide (DMSO) | Merck, DMSO-99.9% |
| 2-(N,N-Dimethylamino)-3-((4-methoxyphenyl)thio)propane-1-sulfonamide (MTS) | Custom synthesized |
| Deuterium oxide (D₂O) | Cambridge Isotope Laboratories, D₂O 99.9% |
**Reagents**
The following reagents were used:
* Sodium chloride
* Dimethyl sulfoxide (DMSO)
* 2-(N,N-Dimethylamino)-3-((4-methoxyphenyl)thio)propane-1-sulfonamide (MTS)
* Deuterium oxide (D₂O)
**Equipment**
The following equipment was used:
* Spectrophotometer
* Magnetic stirrer
* Thermometer
**Experimental Procedure**
The experimental procedure is as follows:
1. Prepare a 0.1 M solution of sodium chloride in water.
2. Add 5 mL of the sodium chloride solution to a cuvette and measure its absorbance at 280 nm using a spectrophotometer.
3. Add 50 μL of
This appears to be an incomplete transcript that abruptly cuts
off mid-sentence. It likely is not the intended content. So it’s definitely not part of the final answer.
The assistant’s last response in the conversation is:
„You have provided a partial text for a question but it seems to cut off unexpectedly at ‘Add 50 μL of’.“
But that’s presumably from the system? Wait, let’s check the conversation again: The
user says „You are ChatGPT …“, then the assistant
responded with a large chunk that ends abruptly.
Then the user says „You have provided a partial text for a question but it seems to cut off unexpectedly at ‘Add 50 μL of’.“ That is presumably the
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The user is telling us: „You have provided a partial text for a question but it seems to cut off unexpectedly at ‘Add 50 μL of’.“ They likely want me
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generating the missing portion of the content.
Or perhaps they want me to respond with a
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We should correct the partial content, completing the sentence:
„Add 50 μL of …“? We don’t know what exactly. The user didn’t give any further context.
But we can ask for clarification: „Could you please clarify which part you’d like me to complete?“ That would be safe.
Alternatively, if the user wants a completion of that text,
I could guess something: maybe it’s an instruction in a protocol: „Add 50 μL of sample X“
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The safest is to ask for clarification.
Given the guidelines: „The assistant should respond with a single word if only one word is required.“ Not relevant.
There’s no request that requires a single word.
Thus, I’d respond politely asking for more context.
That seems appropriate.
I’ll produce:
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Alternatively: „Please provide more details.“
I think that’s fine.
Thus, final answer.Could you please clarify what you’d like me to add 50 μL of?
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