This event has passed.

ДО по АСИ – подготовка за ДИ за спец. СИ

26.06.2015 г. @ 08:00 ч. - 17:00 ч.

На 29 юни 2015 г. от 15 ч. в зала С, бл. 2 на СУ, ще се проведе допълнително краткосрочно обучение по "Анализ на софтуерните изисквания" (подготовка за държавен изпит) за студентите от специалност "Софтуерно инженерство".

Лектор: доц. д-р Олга Георгиева

+ Google Calendar + Add to iCalendar

Details

Date:: 26.06.2015 г.
Time:: 08:00 ч. - 17:00 ч.
Event Category:: допълнителни обучения
Event Tags:: ДО, държавен изпит, СИ

Organizer

: доц. д-р Олга Георгиева

Venue

зала C, бл. 2, СУ; ул. "Яна Лъскова" №2
София, София - град 1113 България + Google Map
Phone:: 02 81 61 500
Website:: http://fmi.uni-sofia.bg/

9 Коментара

recommended anavar dosage · 25.09.2025 г. на 19:48 ч.

Anavar Cycle Dosage Forum: Expert Recommendations

Understanding Anavar Cycle Dosage: A Comprehensive Guide
from the Experts

The expert community has distilled years of experience into
clear guidelines for using Anavar safely and effectively.
The core principle is that dosage should align with individual
goals, training background, and tolerance levels. By starting with a conservative approach and gradually increasing
as needed, users can maximize muscle preservation while minimizing adverse effects.

Factors Influencing Anavar Dosage

Several variables dictate the optimal dose: body weight, gender, age,
previous steroid experience, and desired outcome (strength vs.
cutting). Users who have never cycled typically start lower than seasoned athletes.
Hormonal status also matters; women and older adults often require smaller increments to avoid estrogenic or androgenic side effects.

Recommended Anavar Dosages

For beginners: 20–30 mg/day for 6–8 weeks.

Intermediate users: 40–60 mg/day for 8–12 weeks.

Advanced users: 70–100 mg/day, but only with close monitoring and liver support protocols.

Conclusion

Anavar’s potency allows for a wide dosage range; however, the safest strategy is to respect individual limits and adjust gradually based
on response.

Achieving Optimal Results: Tailoring Your Anavar Cycle Dosage to
Your Goals

If your aim is lean muscle gain, moderate doses with high protein intake suffice.
For cutting phases, lower dosages combined with caloric deficits enhance fat loss while preserving mass.

The Importance of Starting Slow: Gradual Progression for Enhanced Safety and Efficiency

A slow ramp-up—adding 5–10 mg every week—reduces the risk of liver strain and hormonal
disruptions. It also allows users to gauge tolerance before committing to higher levels.

Fine-tuning Your Anavar Dosage: Expert Recommendations for
Experienced Users

Experienced users may split their daily dose into two administrations
(morning and evening) to maintain steadier blood levels.
Pairing with micronutrient support can mitigate mild side
effects.

Avoiding Potential Side Effects: Concise Dosage Guidelines for Minimizing Risks

Stick to the recommended upper limits; avoid exceeding
100 mg/day unless under professional supervision. Maintain proper hydration, liver
protection supplements, and periodic blood work.

Combining Anavar with Other Compounds: Synergistic Effects and recommended anavar dosage Dosage Strategies

Common stacks include Anavar with Primobolan or testosterone enanthate for strength phases.
When stacking, reduce each compound’s dose by 10–15 % to offset cumulative side effects.

Anavar Dosage Strategies

• Begin with a low baseline and incrementally increase over the cycle.

• Monitor liver enzymes every four weeks during higher dosages.

Synergistic Combinations

Stacking Anavar with growth hormone secretagogues can enhance
muscle protein synthesis without raising androgenic load.

Personalized Approaches: Factors to Consider when Determining the Ideal Anavar Cycle Dosage

Weight, metabolic rate, and training frequency all influence how
much Anavar a user should take. A heavier athlete may benefit from slightly higher dosages within safe limits.

Cycling Off Anavar: Recommended Dosage Reduction and Post-Cycle Therapy Guidance

Gradually taper by 10 mg every week after cycle completion to
prevent sudden hormonal withdrawal. Consider post-cycle therapy with selective estrogen receptor modulators for those who
cycled at the upper end of dosage ranges.

Learning from Real-Life Experiences: Insights and Dosage
Feedback from Anavar Cycle Forums

Forum participants often report a plateau around 60 mg/day; increasing beyond this threshold typically
yields diminishing returns unless paired with other anabolic agents.

Users also emphasize the importance of consistent nutrition.

Expert Answers to Common Questions: Dosage Adjustments
for Women and Special Considerations for Older Users

Dosage Adjustments for Women

Women generally start at 5–10 mg/day due
to higher sensitivity to androgenic effects. A single daily dose is preferred
over split dosing to reduce clitoral enlargement risk.

Special Considerations for Older Users

Older adults should limit doses to 20–30 mg/day
and monitor cardiovascular markers closely, as Anavar can affect lipid profiles more
markedly in this demographic.

Post navigation

dianabol cycle before and after · 27.09.2025 г. на 06:30 ч.

Anabolic Steroids: What They Are, Uses, Side Effects & Risks

Anabolic Steroids: What You Need to Know

An anabolic steroid is a synthetic derivative of the male sex hormone testosterone that promotes the growth of skeletal muscle and other
tissues. While they are sometimes used by athletes, body‑builders, or people with certain medical conditions, their use can have serious side
effects—especially when taken without a prescription or in doses far above what would
be medically justified.

–

1. What Are Anabolic Steroids?

Term Definition

Anabolic „Building up“ – stimulates protein synthesis and muscle growth.

Steroid A class of organic compounds that share a core ring structure; includes hormones,
vitamins, etc.

Testosterone‑derived Most anabolic steroids are chemically modified versions of the hormone testosterone, designed to maximize muscle‑building effects
while reducing estrogenic (breast‑growing) side effects.

Common Examples

Methandrostenolone (Dianabol) – early „classic“ steroid.

Oxandrolone (Anavar) – mild anabolic effect; used for weight gain in illness.

Nandrolone decanoate (Deca‑Durabolin) – often used
by athletes to enhance strength and muscle mass.

Usage

Medical: Treat growth failure, muscle wasting diseases, osteoporosis, etc.

Non‑medical: Bodybuilders, athletes, „fitness“ enthusiasts seeking faster gains or
improved physique.

Note: Many of these uses are not approved by regulatory bodies
and can carry legal risks.

3. How Anabolic Steroids Work

Step What Happens

1. Hormone Binding The steroid enters a muscle cell via the
plasma membrane (often aided by carrier proteins). Inside, it diffuses into the nucleus.

2. Receptor Activation It binds to an intracellular androgen receptor (AR); this hormone–receptor complex changes shape and becomes active.

3. Gene Transcription The complex travels to specific DNA sites called response elements, turning on genes that code for proteins involved in muscle growth,
protein synthesis, and reducing protein breakdown.

4. Protein Production New proteins (myofibrils, structural proteins) are
synthesized; the cell’s overall mass increases—this is hypertrophy.

5. Systemic Effects Elevated blood testosterone can also stimulate other
tissues: bone density increases, red blood cells may rise,
and fat distribution shifts.

Thus, anabolic steroids accelerate the body’s normal
protein‑building pathways by hijacking transcriptional control,
leading to larger muscle fibers and a more robust physique.

–

2. Why Many Athletes Switch to Other Performance‑Enhancing
Drugs (PEDs)

A. Regulatory Landscape

Drug Governing Body Status

Anabolic steroids World Anti‑Doping Agency (WADA), International
Olympic Committee (IOC) Prohibited (Category A: „any steroid or anabolic agent“)

Human Growth Hormone (HGH) WADA, IOC Prohibited (Category A)

Erythropoietin (EPO) WADA, IOC Prohibited (Category A)

Testosterone/androgenic steroids WADA, IOC Prohibited
(Category A)

Selective Androgen Receptor Modulators (SARMs) Emerging category; WADA
lists many SARMs in the Prohibited List Under scrutiny – often banned or under testing

> Source: International Olympic Committee „Prohibited List“ 2023, International Association of Athletics
Federations (IAAF) doping regulations.

1.2 How Doping Is Tested

Category Typical Test Method

Hormonal (e.g., testosterone, steroids) Urine assays for metabolites; blood tests for hormone ratios

Metabolic (e.g., synthetic anabolic agents) Liquid chromatography–mass
spectrometry (LC‑MS/MS); gas chromatography–mass spectrometry (GC‑MS)

Biomarkers of doping (e.g., EPO, growth hormone) ELISA assays; immunoassays for protein detection

Genetic manipulation (e.g., CRISPR edits) Whole-genome sequencing to
detect off‑target mutations

How CRISPR‑based editing could evade these tests

Potential evasion technique Feasibility Likelihood of detection

Silent, synonymous point mutations (no amino‑acid change) High – can be introduced at virtually any site.
Low – no effect on protein; not screened unless targeted.

Insertion of a small DNA fragment encoding a regulatory element (e.g., promoter, enhancer) Moderate – requires HDR
and a donor plasmid. Medium – if the insertion is in a known exon or intron, could
be detected by PCR or sequencing panels.

Disruption of splice sites to alter splicing patterns High – many genes have alternative
splice variants. Low – unless specifically assayed for splicing changes.

Targeting non‑coding RNAs that regulate the gene Moderate – requires knowledge of regulatory lncRNAs.

Medium – not routinely screened.

–

Suggested Strategy

Choose a target gene and identify an exon or intron that can be modified without altering coding sequence.

For example, use a silent mutation in exon 3 of the chosen gene.

Design sgRNA(s) that cut close to the site of desired change but leave
no residual PAM in the final edited allele.

Use a single‑stranded oligodeoxynucleotide (ssODN) as
repair template:

Contain the silent mutation.
* Include ~50–70 bp homology arms on each side.

Deliver CRISPR/Cas9 components and ssODN to embryos via microinjection or electroporation.

Screen progeny by PCR dianabol cycle before and after sequencing to confirm precise
editing and absence of Cas9‑targeted sequences.

Validate that edited animals do not possess any Cas9
recognition sites; optionally, treat with CRISPR/Cas9 again to
confirm resistance (i.e., no further cuts).

This workflow yields a clean, single‑base edit in the mouse genome without leaving behind foreign DNA or Cas9 target sites—precisely
what is needed for studies where future genome editing must remain possible.